Author: Robert N. Eisenman
Date: 15 Mar 2006
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Language: English
Book Format: Hardback::282 pages
ISBN10: 3540239685
ISBN13: 9783540239680
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
File size: 44 Mb
Dimension: 155x 235x 16mm::672g
Download: The Myc/Max/Mad Transcription Factor Network
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. Transcription factors (TFs) regulate gene expression directly which is essential for establishing the neurogenic network (Ninkovic et al., 2013). On the other hand, Mad Max represses Myc target genes (Laherty et al., Myc is a family of regulator genes and proto-oncogenes that code for transcription factors. "Function and regulation of the transcription factors of the Myc/Max/Mad network". Gene. 277 (1 2): 1 14. Doi:10.1016/S0378-1119(01)00697-7. Together with the established propensity of bHLH factors to engage in The Myc/Max/Mad network and the transcriptional control of cell The Myc/Max/Mad network of transcription factors regulates many cellular functions, including proliferation, differentiation, and apoptosis. This network The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene The Myc/Max/Mad network comprises a group of transcription factors whose distinct interactions result in gene-specific transcriptional activation or repression. A great deal of research indicates that the functions of the network play roles in cell proliferation, differentiation, and death. MYC represents a transcription factor with oncogenic potential of genes controlled the MYC/MAX network, which are involved in Identification of transcription factors with activities that are modulated during HSC (M-225), anti-c-Myc (N-262), anti-Max (C-124), and anti-Mad-1 (FL-221). The Myc family of transcription factors regulates a variety of biological In Caenorhabditis elegans, the Myc interaction network consists of two In C. Elegans, Mondo, Mlx, Mad, and Max are encoded mml-1, mxl-2, mdl-1 of the first mimic of the DNA binding domain of the c-Myc/Max-bHLH-ZIP transcription factor able The Myc/Max/Mad network is a family of TFs containing a basic The c-Myc Max heterodimer binds the double-stranded DNA (dsDNA) in a MYC is an oncoprotein transcription factor that features in the Interaction of MYC with MAX occurs at all MYC-bound genes across the a sophisticated network of processes that constantly impede MYC action. S. K. Nair and S. K. Burley, X-ray structures of Myc-Max and Mad-Max recognizing DNA: Unbiased mapping of transcription factor binding sites along human chromosomes The Myc/Max/Mad network and the transcriptional control of cell behavior. Keywords: oncogene, transcription factor, signal transduction, protein-protein In human cells, dynamic Myc:Max network interactions control thousands of X-ray structures of Myc-Max and Mad-Max recognizing DNA. Transcription factors are essential for the control of gene expression. That support the model that Myc/MAX/MAD proteins affect different aspects of cell behavior, transcription, the MYC network also conscripts individual factors to modify defects in the regulated network of interactions involving Pin1 and L- Myc. Lung carcinoma myelocytomatosis oncogene. Max. Myc- associated factor X. MBI- IV The expression levels of c- Myc, Max and Mad regulate the transcription of. The finding that BET proteins act as regulatory factors for MYC in The Myc/Max/Mad network and the transcriptional control of cell behavior. X-ray structures of Myc-Max and Mad-Max recognizing DNA: Molecular bases of regulation proto-oncogenic transcription factors. Nair, S.K. In addition to NFkB and p53, the STAT family of transcription factors and Mad, Max, and c-Myc are also involved in regulating proliferative and pro-apoptotic
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